ClpP inhibitor M21
CAS No. 1151944-58-9
ClpP inhibitor M21 ( —— )
Catalog No. M10535 CAS No. 1151944-58-9
ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameClpP inhibitor M21
-
NoteResearch use only, not for human use.
-
Brief DescriptionClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM.
-
DescriptionClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay; alters α-toxin expression in a ClpP-dependent manner and attenuate S. aureus virulence via ClpP inhibition; blocks the pathogenicity of infection in animal models.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorAntibacterial
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1151944-58-9
-
Formula Weight385.45
-
Molecular FormulaC19H15NO4S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC=C(C=C1)COC2=CC=C(C=C2)C=C3C(=O)N(C(=S)S3)CC(=O)O
-
Chemical Name(Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
PBP 10
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.
-
NITD-304
NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.
-
D-3-Phenyllactic aci...
D-3-Phenyllactic acid is an anti-bacterial agent excreted by Geotrichum candidum inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans.