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ClpP inhibitor M21
CAS No. 1151944-58-9
ClpP inhibitor M21( —— )
Catalog No. M10535 CAS No. 1151944-58-9
ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameClpP inhibitor M21
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NoteResearch use only, not for human use.
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Brief DescriptionClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM.
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DescriptionClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay; alters α-toxin expression in a ClpP-dependent manner and attenuate S. aureus virulence via ClpP inhibition; blocks the pathogenicity of infection in animal models.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1151944-58-9
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Formula Weight385.452
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Molecular FormulaC19H15NO4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC=C(C=C1)COC2=CC=C(C=C2)C=C3C(=O)N(C(=S)S3)CC(=O)O
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Chemical Name(Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gao P, et al. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520.
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